The relationship between dietary inflammatory index values and thyroid function in the US adult population: An analysis of the NHANES 2007–2012 cohort

Abstract Objective Researchers have developed the Dietary Inflammatory Index (DII) as a tool to quantify inflammatory potential of given diet. Higher DII scores indicated more proinflammatory While inflammation is known strong impact on thyroid function, precise nature association between and function has yet be clarified. This study was conducted with goal exploring this relationship in representative population adults from United States. Methods For study, we used data National Health Nutrition Examination Survey (NHANES). Standardized questionnaires were collect demographic dietary participants, laboratory tests participants' parameters other relevant data. Linear regression models smoothed curve fitting assess weighted analyses subgroup being appropriate. Results In total, 7712 subjects recruited NHANES 2007–2012 cohort. Their mean age 44.87 (0.47) years, score 1.41 (0.05). Mean FT3 3.20 (0.01) pg/mL TT4 7.81 (0.03) µg/dL. adjusted analyses, higher values related increases ( β = .007; p .027) .050; .005) levels. Subgroup showed negative correlation levels high urinary iodine concentrations. Conclusion These indicate that consumption diet, evidenced by elevated scores, correlated significant However, for people concentrations, diet associated lower Additional research will vital clarify mechanistic basis these findings.